Ractopamine is an animal feed additive used to promote leanness and increase food conversion efficiency in livestock in some countries, but banned in others. As of 2014 the use of ractopamines was banned in 160 countries, including the European Union, mainland China and Russia. In the U.S., ractoamine is allowed to be used at a feed concentration of 5–20 mgkg feed for finishing pigs and in dosages of 5-10 mg kg feed for heavier than 109 kg.
About Ractopamine in brief
Ractopamine is an animal feed additive used to promote leanness and increase food conversion efficiency in livestock in some countries, but banned in others. It is a phenol-based TAAR1 agonist and β adrenoreceptor agonist that stimulates β1 and β2 adrenergic receptors. It was developed by Elanco Animal Health, a division of Eli Lilly and Company. As of 2014 the use of ractopamines was banned in 160 countries, including the European Union, mainland China and Russia. 27 other countries, such as Japan, the United States, South Korea, and New Zealand have deemed meat from livestock fed ractsopamine safe for human consumption. In the U.S., ractoamine is allowed to be used at a feed concentration of 5–20 mgkg feed for finishing pigs and in dosages of 5-10 mg kg feed for heavier than 109 kg. The maximum residue limit for ractotamine for meat in the USA is 50 parts per billion, or five times the standard set by the Codex Alimentarius. In 2015, the USDA approved of a new label, \”No beta-agonist — a promotant of growth — to be use in turkeys and swine, backed up by a randomized testing policy. Currently, no synthetic compounds can be used on the label. The Canadian Racto-Free Pork Certification Program maintains the CFIA-Free Certification Program so that Canadian exports to Asian countries are not disallowed by their authorities. Hundreds of commercial feed facilities, including some in Canada, are not allowed to use Ractopamine.
Some of these facilities are enrolled in the CRFP, a programme that is essentially based on a self-certification and randomized testing programme on organic compounds, including those other than those on the USDA list. The US Food and Drug Administration (FDA) does not allow synthetic compounds on its label, including synthetic compounds that are not on its list of approved organic compounds. The FDA has no plans to change its policy on the labeling of organic compounds on the US label, which is based on the randomized testing and backed up on a program that is basically based on randomized testing by the USDA. In cattle on 28 January 2004 Elanco. Animal Healthmade Optaflexx commercially available in the US. It is labeled only for use in steers or market heifers during the last 28-42 days on feed. Its use in finishing swine yields about 3 kg of additional lean pork and improves feed efficiency by 10%. In cattle in 1999 the FDA approved the FDA-approved swine swine additive, in 1999 in cattle in cattle, and in 2008 for use in turkey inturkeys. In Canada, the US, Canada, and Mexico, ractOpamine use as a feed additive is authorized in the United. States, Canada and Mexico. Ract Opamine is also a positional isomer of dobutamine, a related drug. When used as a food additive, it can be distributed by the blood to the muscle tissues, where it serves as a full agonist.