Paolo Macchiarini

Paolo Macchiarini

Paolo Macchiarini is a Swiss-born Italian thoracic surgeon and a former researcher on regenerative medicine. He became known for research fraud and manipulative behavior. Seven of the eight patients who received one of his synthetic trachea transplants have died. As of 2020, he has had eight of his research papers retracted, and two have received an expression of concern.

About Paolo Macchiarini in brief

Summary Paolo MacchiariniPaolo Macchiarini is a Swiss-born Italian thoracic surgeon and a former researcher on regenerative medicine. He became known for research fraud and manipulative behavior. He has been accused of research misconduct and unethically performing experimental surgeries, even on relatively healthy patients. Seven of the eight patients who received one of his synthetic trachea transplants have died. As of 2020, he has had eight of his research papers retracted, and two have received an expression of concern. He worked at the Kazan Federal University in Russia, until the university terminated his project in April 2017, effectively firing him. He was an investigator at the Institut d’Investigacions Biomèdiques-Instituto de Investigaciones Biomédicas in Barcelona from 2006 to 2009; he was affiliated with but not an employee of University of Barcelona and was apparently an employee at the Hospital Clínic de Barcelona during this time. He had an honorary appointment as a Visiting Professor from 2009 to 2014 at University College London. He is married to the former head of the department of surgery at the Heidehaus Hanover hospital in Germany, and has a son and a daughter. He lives in Switzerland with his wife and two children. He received a Master of Surgery from the University of Pisa, Italy in 1986. He obtained a masters in organ and tissue transplantation dated 1994 and a doctorate in the same dated 1997, from University of Franche-Comté. In 2008, he moved to Russia with an honorary doctorate from the Russian State Medical University and the university funded by the Russian government, along with an Honorary Doctorate in Organ and Tissue Transplantation.

In 2010, he was appointed as a visiting professor at the Karolinska Institute in 2010, and as a part-time position as surgeon at the affiliated university hospital. In 2013 Karlinska terminated its clinical relationship with MacchiARini but allowed him to continue as a researcher. In April 2017 the university moved him to Kazan Federal University and terminated his research project there. The attorney general’s office announced in October 2017 that Macchiarini had been negligent in four of the five cases investigated due to the use of devices and procedures not supported by evidence, but that a crime could not be proven because the patients might have died under any other treatment given. In October, Sweden’s national scientific review board found scientific misconduct by Maccharini and his co-authors in six papers about the procedures, and called for them to be retracted. The secretary of the Nobel Committee for Physiology or Medicine, Urban Lendahl, resigned in February 2016, owing to his involvement in recruiting Macchirini to Karolin’s Institutet in 2010. In February 2016 Karol inska announced that it would not renew Macchiarini’s research contract, which was due to expire in November, and the next month Karolska terminated the contract due to incomplete results.