Helicobacter pylori is a gram-negative, microaerophilic, spiral bacterium usually found in the stomach. Up to 90% of people infected with H. pyleori never experience symptoms or complications. Individuals infected with the bacteria have a 10% to 20% lifetime risk of developing peptic ulcers. It can cause multiple sclerosis, coronary artery disease, periodontitis, Parkinson’s disease, Guillain–Barré syndrome.
About Helicobacter pylori in brief
Helicobacter pylori is a gram-negative, microaerophilic, spiral bacterium usually found in the stomach. H. pylori infection usually has no symptoms but sometimes causes gastritis or ulcers of the stomach or first part of the small intestine. The infection is also associated with the development of certain cancers occurring in less than 20% of cases. In 2015, it was estimated that over 50% of the world’s population had H. Pylori in their upper gastrointestinal tracts with this infection being more common in developing countries. Up to 90% of people infected with H. pyleori never experience symptoms or complications. However, individuals infected with the bacteria have a 10% to 20% lifetime risk of developing peptic ulcers. The bacterial infection has also been proposed to have protective effects for its hosts against infections by other pathogens, asthma, obesity, celiac disease, inflammatory bowel disease, rhinitis, atopic dermatitis, gastroesophageal reflux disease, and esophagesal cancer. Some studies suggest that H pylora plays an important role in the natural stomach ecology, e. g. by influencing the type of bacteria that colonize the gastrointestinal tract. Others suggest that non-pathogenic strains of H.elaerophilic H.P. may beneficially normalize stomach acid secretion, and regulate appetite. In recent decades, however, the prevalence of H.
pyleori colonization of the gastrointestinal tract has declined in many countries. It is still common in some countries, but it has declined significantly in recent years. The bacterium was first identified in 1982 by Australian doctors Barry Marshall and Robin Warren. It can cause multiple sclerosis, coronary artery disease, periodontitis, Parkinson’s disease, Guillain–Barré syndrome, rosacea, psoriasis, chronic urticaria, spot baldness, various autoimmune skin diseases, Henoch–Schönlein purpura, low blood levels of vitamin B12, autoimmune neutropenia, the antiphospholipid syndrome, plasma cell dyscrasias, open angle glaucoma, blepharitis, diabetes mellitus, the metabolic syndrome, various types of allergies, non-alcoholic fatty liver disease, non.alcoholic steatohepatitis, hepatic fibrosis, and liver cancer. The symptoms, if present, are often those of non-ulcer dyspepsia: Stomach pains, nausea, bloating, belching, and sometimes vomiting. Less common ulcer symptoms include nausea, vomiting, and loss of appetite. Bleeding can also occur as evidenced by the passage of black stools; prolonged bleeding may cause anemia leading to weakness and fatigue. Inflammation of the pyloric antrum, which connects the stomach to the duodenum, is more likely to lead to duodenal ulcers, while of the corpus ulcers is more Likely to lead to gastric polyps.
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This page is based on the article Helicobacter pylori published in Wikipedia (as of Dec. 03, 2020) and was automatically summarized using artificial intelligence.
