Molnupiravir

Molnupiravir is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine. It exerts its antiviral action through introduction of copying errors during viral RNA replication. Activity has been demonstrated against coronaviruses including SARS, MERS and SARS-CoV-2.

About Molnupiravir in brief

Summary MolnupiravirMolnupiravir is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine. It exerts its antiviral action through introduction of copying errors during viral RNA replication. Activity has also been demonstrated against coronaviruses including SARS, MERS and SARS-CoV-2.

The drug was developed at Emory University by the university’s drug innovation company, Drug Innovation Ventures. It was then acquired by Miami-based company Ridgeback Biotherapeutics, who later partnered with Merck &