The Siege of Tyre was orchestrated by Alexander the Great in 332 BC during his campaigns against the Persians. The Macedonian army was unable to capture the city because it was on an island. Alexander responded to this problem by first blockading and besieging Tyre for seven months, and then by building a causeway that allowed him to breach the fortifications.
About Siege of Tyre (332 BC) in brief

This gave him command of a new fleet of 80 ships. With his new fleet, Alexander sailed on to Tyre and blockaded the city and its ports. With the arrival of 120 galleys sent by Cyprus, who had heard of his victories and wished to join him, the king of Cyprus sent a fleet of 23 ships to join Alexander’s forces. The city was quickly blockaded and Alexander’s new fleet sailed on and blocked Tyre’s ports, giving him control of both ports and giving him the command of the Greek states of Ionia, Sidon and Issus, which had composed most of the Persian navy. At the time of the siege, the city held approximately 40,000 people, though the women and Children had been evacuated to Carthage.
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