Ivermectin
Ivermectin is a medication used to treat many types of parasite infestations. This includes head lice, scabies, river blindness, strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis. It works by causing the parasite’s cell membrane to increase in permeability, resulting in paralysis and death. Common side effects include red eyes, dry skin, and burning skin. Use in the eyes should be avoided.
About Ivermectin in brief
Ivermectin is a medication used to treat many types of parasite infestations. This includes head lice, scabies, river blindness, strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis. It works by causing the parasite’s cell membrane to increase in permeability, resulting in paralysis and death. Common side effects include red eyes, dry skin, and burning skin. Use in the eyes should be avoided. It is unclear if it is safe for use during pregnancy, but is probably acceptable foruse during breastfeeding. IvermECTin was discovered in 1975 and came into medical use in 1981. It is on the World Health Organization’s List of Essential Medicines. In veterinary medicine, it is used to prevent and treat heartworm and acariasis,. It is as effective as albendazole or alternative antinematode drugs for treatment of pinworm infection. It can be taken by mouth or applied to the skin for external infestation. It does not kill adult worms. A single oral dose, taken once or twice a year for the 10–15-year lifespan of the adult worms, is required to protect the individual from river blindness.
Moxidectin has been approved by the FDA for use in people with river blindness and has a longer half-life. It may eventually supplant iver mectin, as it is a more potent microfilaricide. It has fewer adverse effects than does thiabendazoles and is at least as well tolerated as al bendazol. It could be cost effective for people moving to Europe from areas where threadworm is common to be given a single-dose of iverMectin on arrival so as to cure presumptive infection with threadworm. People who are immunocompromised or who will receive immunosuppressive treatment and who have confirmed or presumptive threadworm infestation are likely to benefit from treatment with ivermector. Combination therapy with iversectin plus albENDazole is effective for treatment of whipworm. Evidence supports its use against parasitic arthropods and rosacea in Europe, as well as in the U.S. A review found that ivernectin was more effective than alternatives for treatment for papulustular acne. In a clinical study, iverin reduced lesions by 83% over 4 months compared to 74% under a metronidazole.
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This page is based on the article Ivermectin published in Wikipedia (as of Jan. 01, 2021) and was automatically summarized using artificial intelligence.