Rhabdomyolysis
Rhabdomyolysis is a condition in which damaged skeletal muscle breaks down rapidly. Symptoms may include muscle pains, weakness, vomiting, and confusion. Outcomes are generally good if treated early. RhabdomYolysis occurs in about 26,000 people a year in the United States.
About Rhabdomyolysis in brief
Rhabdomyolysis is a condition in which damaged skeletal muscle breaks down rapidly. Symptoms may include muscle pains, weakness, vomiting, and confusion. The muscle damage is most often the result of a crush injury, strenuous exercise, medications, or drug abuse. Other causes include infections, electrical injury, heat stroke, prolonged immobilization, lack of blood flow to a limb, or snake bites. Outcomes are generally good if treated early. Complications may include high blood potassium, low blood calcium, disseminated intravascular coagulation, and compartment syndrome. RhabdomYolysis occurs in about 26,000 people a year in the United States. Some have an underlying muscle condition, usually hereditary in nature, that makes them more prone to rhabdomoolysis. Poisons linked to the condition are heavy metals and venom from insects or snakes. Haff disease is a toxic cause; consuming fish; alcohol, alcohol, heroin, ketamine, cocaine and MDMA are all potential causes. Recurrent rhab Domolysis may result from intrinsic muscle enzyme deficiencies, which often appear during childhood and are usually inherited during childhood. Crush and other muscle injuries may take various forms and interfere with physical damage to skeletal muscle. Inherited muscle disorders and infections together cause the majority of rhab domolytic injuries. The majority of hereditary muscle disorders in children are usually caused by exertional muscle damage or other forms of physical damage that interfere with the ability to exertional exercise or other physical damage. The mainstay of treatment is large quantities of intravenous fluids.
Other treatments may include dialysis or hemofiltration in more severe cases. The urine may be dark, often described as \”tea-colored\”, due to the presence of myoglobin. Swelling of damaged muscle occasionally leads to compartment syndrome—compression of surrounding tissues, such as nerves and blood vessels, in the same fascial compartment—leading to the loss of blood supply and damage or loss of function in the part of the body supplied by these structures. It is a significant problem for those injured in earthquakes, and relief efforts for such disasters often include medical teams equipped to treat survivors with rhabDomyolytic injury. The diagnosis is supported by a urine test strip which is positive for \”blood\” but the urine contains no red blood cells when examined with a microscope. Milder forms may not cause any muscle symptoms, and the diagnosis is based on abnormal blood tests in the context of other problems such as blood pressure or heart rate and rhythm. If the swelling is very rapid, the movement of fluid from the bloodstream into damaged muscle may cause low blood pressure and shock. Other symptoms are nonspecific and result either from the consequences of muscle tissue breakdown or from the condition that originally led to the muscle breakdown. If kidney failure develops, sodium bicarbonate and mannitol are commonly used but they are poorly supported by the evidence. Once urine output is established, sodium bic carbonate andMannitol are commonly used.
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This page is based on the article Rhabdomyolysis published in Wikipedia (as of Dec. 03, 2020) and was automatically summarized using artificial intelligence.
